New Drug Approach Could Lead to Cures for Wide Range of Diseases

http://www.sciencedaily.com/releases/2013/12/131209181101.htm

An article saying that a number of diseases are caused by protein misfolding, including Alzheimer's.

If you can get information on which proteins are misfolded, you may want to start simulations of the misfolding, and then add some simulations of what substances bound to the misfolded proteins do or do not restore their normal functions.

Names a few misfolded proteins:
An error in protein conformation can lead to disease. What are the genetic and molecular causes for incorrectly formed proteins?
http://www.nature.com/scitable/topicpage/protein-misfolding-and-degenerative-diseases-14434929

another article you have to pay for if you want to read it:
protein misfolding
http://www.nature.com/nature/insights/6968.html