Perhaps the investment is the supercomputers at Los Alamos are already showing results:

http://www.hpcwire.com/offthewire/Scientists-Ratchet-Up-Understanding-of-Cellular-Protein-Factory-111146994.html

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Running Microsoft's "System Idle Process" will never help cure cancer, AIDS nor Alzheimer's. But running Rosetta@home just might!
https://boinc.bakerlab.org/rosetta/