Types of WU's and Their Nomenclature

Message boards : Rosetta@home Science : Types of WU's and Their Nomenclature

To post messages, you must log in.

AuthorMessage
Profile Cesium_133*
Avatar

Send message
Joined: 1 Dec 08
Posts: 28
Credit: 225,332
RAC: 0
Message 63606 - Posted: 5 Oct 2009, 4:33:40 UTC

Seems that Rosetta is working well now, and I'm glad to be back on board after an absence.

I'm interested in what the WU codes and abbreviations mean. I know that a fair bit of it is just unit numbering and call-signs as to what researchers should look at and what the WU is doing, but as to...

lr8_combine_smooth_torsion...IGNORE_THE_REST_DECOY,

Rossmann2X3...

symm_lr8... and

histone_loopbuild...,

can anyone explain these WUs' procedures in reasonably simple terms? They look like football play calls :p I've seen many other codings as well, and if anyone could post them or tell me where to look for an explanation, I'd be appreciative. I'm very interested in this kind of thing :)
The lovely lady you see isn't I, but Hayley Westenra, a classical crossover singer from Christchurch, NZ. There is no known voice as hers. Check her out- she's seraphic.

ID: 63606 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile Morten Starkeby
Avatar

Send message
Joined: 18 Feb 06
Posts: 10
Credit: 472,142
RAC: 0
Message 63607 - Posted: 5 Oct 2009, 4:46:52 UTC
Last modified: 5 Oct 2009, 4:56:40 UTC

This thread should help you a bit on the way:

https://boinc.bakerlab.org/rosetta/forum_thread.php?id=1453
ID: 63607 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile Cesium_133*
Avatar

Send message
Joined: 1 Dec 08
Posts: 28
Credit: 225,332
RAC: 0
Message 63608 - Posted: 5 Oct 2009, 5:49:41 UTC

Bugger all, that's some advanced microbiology... thanks, Morten, for the direction. Obviously, understanding any useful amount of that is contingent on having a degree in cellular chemistry, organic chemistry, or something similar dealing with high-level biochemistry/biophysiology/biophysics. I'm just glad I know what tyrosine and tryptophan are.

However, as I don't want simply to be a lackey, unaware of what I am really doing to help, I shall start from the beginning and try to get my mind around what all that chemical and molecular jargon means. I know simple stuff about DNA... codons, triplets, mRNA, tRNA, rRNA, and such, so I might be able to become 1/4 conversant in this field...

But I warn everyone... this subject looks pretty ferocious and complex. Be warned... those tentacles coming off the main DNA trunk might sting... :p
The lovely lady you see isn't I, but Hayley Westenra, a classical crossover singer from Christchurch, NZ. There is no known voice as hers. Check her out- she's seraphic.

ID: 63608 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Michael G.R.

Send message
Joined: 11 Nov 05
Posts: 264
Credit: 11,247,510
RAC: 0
Message 63621 - Posted: 7 Oct 2009, 5:02:55 UTC

Wikipedia's a good place to start. Just look up the stuff you don't understand.

But if you want to dig deeper, you can do what I did and get "Molecular Biology of the Cell" (5th ed) by Alberts & Al.
ID: 63621 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile robertmiles

Send message
Joined: 16 Jun 08
Posts: 1232
Credit: 14,274,116
RAC: 1,462
Message 63659 - Posted: 13 Oct 2009, 11:17:31 UTC
Last modified: 13 Oct 2009, 11:30:30 UTC

See this article on why workunits with histone as part of their names are likely to be useful:


Trial drugs 'reverse' Alzheimer's

http://news.bbc.co.uk/2/hi/health/8033422.stm


Or, if you prefer, do as I did and insert histone into the box before Search forums above the start of this thread, then click on the Search forums box, and get a list of posts that at least mention histone, then check which of them say or give a link to something useful about histones.

Also try it with torsion.
ID: 63659 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote

Message boards : Rosetta@home Science : Types of WU's and Their Nomenclature



©2024 University of Washington
https://www.bakerlab.org