Has all of the data crunching resulted in any medical breakthroughs?

---

You can read in David Baker's Journal, that he and his team are working on two papers about the proteins crunched last summer and one paper about the HPF project phase 1 based on Rosetta, which ran on the World Community Grid.

---

So rosetta is searching for optimization of protein prediction and HPF searched for medical applications based on the rosetta structure ?

---

So rosetta is searching for optimization of protein prediction and HPF searched for medical applications based on the rosetta structure ?

That puts it pretty well, yes. Rosetta is working to find the structure accurately and quickly, and others are focused on applying that knowledge to solve specific disease or create vaccines.

But, in addition to that primary focus, Rosetta is also working on AIDS specifically with the GP120 work units. And the DOC (docking) work units are taking on the difficult problem of how the structures of two proteins will be effected when placed next to each other, and whether there will be enough energy for them to attract one another and bind together. This technology will some day be used to create very targetted treatments for specific viruses.

And that distinction is part of why I did not respond to Thomas' original question as stated. You see, the goal here on R@h is not one specific medical breakthrough. But once we master the protein structure prediction problem, then the entire field of medicine is changed forever.

---

Rosetta Moderator: Mod.Sense

... But once we master the protein structure prediction problem, then the entire field of medicine is changed forever.

I like your optimism, but I'm conservative by nature. Having majored in chemistry (though computer programming was my trade) I view our searches as a bit like climbing a mountain of sand...you will move forward and upward but the nature of sand makes it an arduous struggle.

... But once we master the protein structure prediction problem, then the entire field of medicine is changed forever.

I like your optimism, but I'm conservative by nature. Having majored in chemistry (though computer programming was my trade) I view our searches as a bit like climbing a mountain of sand...you will move forward and upward but the nature of sand makes it an arduous struggle.

Of course with a bit of Chemistry you can make a mountain of sand in to something much easier to climb ;-) or with some surfactant or fungus make nanoparticles out of it... or ...

Either that or just step gently on the sand like and Ant :-D

---

Team mauisun.org

...or you could use the silicon in the sand and make CPUs!

---

Add this signature to your EMail:
Running Microsoft's "System Idle Process" will never help cure cancer, AIDS nor Alzheimer's. But running Rosetta@home just might!
https://boinc.bakerlab.org/rosetta/

Of course with a bit of Chemistry you can make a mountain of sand in to something much easier to climb ;-) or with some surfactant or fungus make nanoparticles out of it... or ...

Touche. The mutation approach has merit WHERE applicable.

Either that or just step gently on the sand like and Ant :-D

The ant clearly has the advantage in my example. Is Rosetta the proverbial ant who can't stop climbing the proverbial rubber tree plant?