Message boards : Rosetta@home Science : Now you can see the CASP7 jobs!
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Rodrigo Send message Joined: 10 Nov 05 Posts: 4 Credit: 51,708 RAC: 0 |
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David Baker Volunteer moderator Project administrator Project developer Project scientist Send message Joined: 17 Sep 05 Posts: 705 Credit: 559,847 RAC: 0 |
in this link: ROBETTA is our public "community service" server that is automatically making predictions for all the casp7 targets. because it takes requests from all over the world, and only has a limited time, it is running our "old" faster protocol which includes only the low resolution part of the search. rosetta@home is running our new combined low and high resolution protocol, and we would expect the results to be much more accurate (but only time will tell!). of course, if the new protocol is consistently better, we will try to make it availalble to the world through ROBETTA, but this will require really large amounts of compute power. In the last casp, many participants simply took the publicly available robetta models and submitted them to casp with only small modifications which was of course fine with us! I think this time the assessors are supposed to put more emphasis on "added value". |
R/B Send message Joined: 8 Dec 05 Posts: 195 Credit: 28,095 RAC: 0 |
I've looked this over..and pardon my ignorance (perhaps others have questions like mine also) but can someone elaborate on these tables more and explain? Thanks..... Founder of BOINC GROUP - Objectivists - Philosophically minded rational data crunchers. |
came203 Send message Joined: 6 May 06 Posts: 2 Credit: 149,712 RAC: 0 |
hi david, could you please clarify how you select models 1-5. i'm just curious because that was the topic of my master's thesis (in casp4). do you just select the 5 best models (lowest energy) or do you have any other strategy ? from my point of view, the bakerlab will win casp7, byt you never know what a certain russian professor has in hand..... |
David Baker Volunteer moderator Project administrator Project developer Project scientist Send message Joined: 17 Sep 05 Posts: 705 Credit: 559,847 RAC: 0 |
hi david, I think it will depend on whether there is a set of similar structures all much lower in energy than all others. (this is what we hope for!). In this case all five models will be from this group and will represent whatever minor structural variation exists. If this is not the case, so we can't be totally confident, we will choose the lowest energy structure, then the next lowest energy structure that is pretty different, and so on. |
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Rosetta@home Science :
Now you can see the CASP7 jobs!
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